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CCRTD FACULTY

Dr. Joann Powell

Home Dr. Joann Powell
Dr. Joann Powell
Assistant Professor
Department of Biological Sciences
Clark Atlanta University
jpowell@cau.edu
Telephone: 404-880-6794
Fax: 404-880-6756
 

Education

B.S.   Alabama A&M University

PhD   Meharry Medical College

Postdoctoral   Emory University School of Medicine; Winship Cancer Institute

Research Interest

Our lab aims to understand the molecular mechanisms by which cancer cells progress into advanced and malignant phenotypes. In particular, we focus on the role of the aryl hydrocarbon receptor (AhR) in prostate cancer progression. AhR is widely known for its role in mediating the harmful effects of a number of environmental toxins. However, evidence suggests that it may also play a key role in the progression of prostate cancer from castration dependent to castration independent. Specific goals of our lab are to: 

1. Determine the role of AhR in the development of castration independent prostate cancer via         interaction with the androgen signaling pathway.
 
2. Investigate the effects of environmental toxins (AhR agonist) on prostate cancer progression.
 
3  Establish AhR as a potential therapeutic target in the treatment of castration independent   prostate cancer.